Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC Quin-C7 | 871100-12-8
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Quin-C7 | 871100-12-8
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Medchemexpress LLC Quinine | 130-95-0 | 99.8% | 10 G
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Quinine is an alkaloid derived from the bark of the cinchona tree, acting as an anti-malaria agent. It functions as a potassium channel inhibitor, specifically inhibiting WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV with an IC50 of 169 μM. It is for research use only and not sold to patients.
- Anti-malaria agent
- Potassium channel inhibitor (inhibits WT mouse Slo3 (KCa5.1) channel currents with an IC50 of 169 μM)
- Inhibits DENV virus replication in HepG2 cells
- Reduces DENV-positive cells in a dose-dependent manner
- Shows tumor-suppressing effects on skin cancer in Swiss albino mice
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Medchemexpress LLC Quinidine methiodide | 42982-87-6 | C21H27IN2O2 | 25 MG
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Quinidine methiodide is a metabolite of Quinidine, an antiarrhythmic agent, intended for research use only. This high-purity product, appearing as a white to light yellow solid, requires specific storage conditions to maintain its integrity.
- Metabolite of Quinidine, an antiarrhythmic agent
- For research use only
- Purity of 99.75%
- Solid, white to light yellow appearance
- Optimal storage at -20°C under nitrogen, away from moisture
- Solvent storage at -80°C for 6 months or -20°C for 1 month under nitrogen, away from moisture
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 25 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It is a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It can induce apoptosis and is used for malaria research.
- Antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- K+ channel blocker with an IC50 of 19.9 μM
- Induces apoptosis
- Can be used for malaria research
- Shows cytotoxicity against MES-SA cells
- Shows effects on the PTZ-induced seizure threshold in vivo
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Medchemexpress LLC Cinchonidine (α-Quinidine) | 485-71-2 | 99.6% | 294.39 | 25 G
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Cinchonidine is a cinchona alkaloid found in plants such as *Cinchona officinalis*. It serves as a building block in asymmetric synthesis and exhibits antimalarial activities.
- Acts as a weak inhibitor of the serotonin transporter (SERT)
- Used as a building block in asymmetric synthesis
- Exhibits antimalarial activities
- Available in solid, white to off-white appearance
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Medchemexpress LLC TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | MFCD31657341; MFCD26793840 | 99.7% | 432.39 g/mol | C22H27Cl2N5 | 25 MG
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TLR7/8 agonist 1 dihydrochloride is a TLR7/TLR8 dual-agonistic imidazoquinoline salt used as a research tool to activate innate immune signaling in cellular and animal studies. It is supplied as a high-purity solid suitable for in vitro and in vivo formulations.
- High purity: 99.7%.
- Molecular weight: 432.39 g/mol.
- Chemical formula: C22H27Cl2N5.
- Appearance: off-white to white solid.
- Soluble in DMSO: 83.33 mg/mL (requires ultrasonic).
- In vivo formulations: soluble ≥2.08 mg/mL in multiple vehicle systems.
- Storage: 4°C sealed; in solvent -80°C (6 months) or -20°C (1 month).
- Applications: TLR7/8 activation in immunology and pharmacology studies.
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Medchemexpress LLC DBCO-PEG9-amine | 2353409-99-9 | 95.0% | C39H57N3O11 | 25 MG
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DBCO-PEG9-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein intended for degradation. They operate by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains a DBCO group for SPAAC reactions
- Facilitates strain-promoted alkyne-azide cycloaddition with azide groups
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC MPEG-amine (MW 2000) | 80506-64-5 | 99.6% | (C2H4O)nC3H9NO | 100 MG
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MPEG-amine (MW 2000) is a PEG-based PROTAC linker, also known as mPEG-NH2 (MW 2000). It is designed for use in the synthesis of PROTACs. This product is intended for research purposes only.
- White to off-white solid appearance
- Purity of 99.57%
- Soluble in DMSO
- Recommended for sealed storage at 4°C, away from moisture and light
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Medchemexpress LLC 5(6)-carboxy-2',7'-dichlorofluorescein diacetate | 127770-45-0 | 97.5% | 529.28 | C25H14Cl2O9 | 10 MG
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5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell-permeant fluorescent tracer used to detect reactive oxygen species (ROS) in live-cell assays. Supplied as the diacetate ester to enable cellular uptake, intracellular esterases cleave the acetate groups to yield the fluorescent carboxy-dichlorofluorescein. It is commonly used in fluorescence-based assays and live-cell imaging.
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Selleck Chemical LLC WST-8
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WST-8 is a water-soluble tetrazolium salt used for assessing cell metabolic activity that produces corresponding formazan dye that absorbs at 460 nm WST-8 is typically used as a cell viability indicator in cell proliferation assays
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Selleck Chemical LLC 8-Methyltocol
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( )-Delta-Tocopherol (8-Methyltocol) is the orally bioavailable delta form of the naturally-occurring fat-soluble vitamin E mostly found in soybean and corn oils with potential antioxidant activity
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Chemscene ChemScene | 3-Aminoquinoline-8-carboxylic acid | 250MG | CS-0460356 | 0.97 | 1799412-39-7| MFCD28133462 | 188.19
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ChemScene | 3-Aminoquinoline-8-carboxylic acid | 250MG | CS-0460356 | 0.97 | 1799412-39-7| MFCD28133462 | 188.19
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Ambeed 4Aminoisophthalic acid
4-Aminoisophthalic acid, 33890-03-8, 98%
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Ambeed 4 6 2 3Methylbenzylidene hydra
4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate, 870087-36-8, 98%
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Ambeed R 3Fluoropyrrolidine Hydroc
(R)-(-)-3-Fluoropyrrolidine Hydrochloride, 136725-55-8, 98%
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